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Melatonin

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substance Score Unrated 0 ratings— needs ≥ 3 ratings C13H16N2O2 Also on Neurotransmission ↗
Anti-agingAntioxidantEndogenous
⤢ 3D

Melatonin is a hormone that signals darkness and helps set the circadian clock. It is genuinely useful for circadian problems — jet lag and delayed sleep-phase — and modestly shortens time to fall asleep, but it is a weak hypnotic and not a strong treatment for chronic insomnia. It appears safe short-term; long-term effects and optimal dosing are less certain, and product content varies.

Too little may be associated with

Disrupted sleep timing.

Too much may be associated with

Grogginess, vivid dreams, next-day drowsiness.

Informational only — not medical advice.

Benefits

Hormone that signals darkness—useful for jet lag, shift work, and delayed sleep phase, and helps some people fall asleep faster.

Risks

Can cause grogginess, vivid dreams, and headache, and supplements are frequently mislabeled for potency. Long-term and pediatric effects are uncertain—use low doses.

Informational only — not medical advice.

Body systems

Organs

Functions

Hormones

Neurotransmitters

Related

Where to buy

Popular Melatonin products on Amazon. Not medical advice — talk to a clinician before starting a supplement.

As an Amazon Associate, Neurotransmission earns from qualifying purchases.

Research (39)

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