Fasting (short-term)
Brief abstention from food that raises norepinephrine and dopamine.
Too little may be associated with
Stable but less metabolic flexibility.
Too much may be associated with
Low blood sugar, fatigue; risky for some conditions.
Informational only β not medical advice.
Body systems
Organs
Hormones
Neurotransmitters
Related
Books (4)
Podcasts
- The Peter Attia Drive
Peter Attia on longevity, health, exercise, and behavior change.
Research (31)
- Intermittent fasting produces antidepressant-like effects by modulating dopamine D1 receptors in the medial prefrontal cortex Piao et al. (2025) Full text β PubMed β
- Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials Frank (2025) Full text β PubMed β
- Intermittent fasting reduces alpha-synuclein pathology and functional decline in a mouse model of Parkinson's disease SzegΕ et al. (2025) Full text β PubMed β
- Intermittent fasting boosts sexual behavior by limiting the central availability of tryptophan and serotonin Zhou et al. (2025) Full text β PubMed β
- Nutrition, GH/IGF-1 signaling, and cancer Valter (2024) Full text β PubMed β
- Intermittent fasting alerts neurotransmitters and oxidant/antioxidant status in the brain of rats Abdel-Rahman et al. (2024) Full text β PubMed β
- Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner David (2024) Full text β PubMed β
- A Literature Review on Holistic Well-Being and Dopamine Fasting: An Integrated Approach Desai et al. (2024) Full text β PubMed β
- Intermittent fasting disrupts hippocampal-dependent memory and norepinephrine content in aged male and female mice Wiersielis et al. (2024) Full text β PubMed β
- Human trials exploring anti-aging medicines David (2024) Full text β PubMed β
- Nutrition and dietary restrictions in cancer prevention Valter (2024) Full text β PubMed β
- Postprandial Hyperlipidemia: Its Pathophysiology, Diagnosis, Atherogenesis, and Treatments Yanai et al. (2023) Full text β PubMed β
- Nutrition, longevity and disease: From molecular mechanisms to interventions Valter (2022) Full text β PubMed β
- Time-restricted Eating for the Prevention and Management of Metabolic Diseases Satchin (2022) Full text β PubMed β
- Hyperinsulinemia Associated Depression Sarwar et al. (2022) Full text β PubMed β
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