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Vitamin B12

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substance Score Unrated 0 ratings— needs ≥ 3 ratings Also on Neurotransmission ↗

Vitamin B12 is essential for nerve function, DNA synthesis, and neurotransmitter metabolism, and deficiency can cause fatigue, neuropathy, and cognitive or mood changes that supplementation reverses. In people who are not deficient, however, extra B12 has not been shown to boost energy, mood, or cognition. Deficiency is common in older adults, vegans, and those on certain medications.

Too little may be associated with

Deficiency: fatigue, neuropathy, cognitive and mood decline.

Too much may be associated with

Excess generally excreted; usually safe.

Informational only — not medical advice.

Benefits

Essential for nerve function, DNA synthesis, and red-cell formation; supplementation prevents and treats deficiency common in vegans and older adults.

Risks

Very safe (water-soluble, with excess excreted); injections are prescription. High doses can mask deficiency symptoms and rarely trigger acne or rosacea flares.

Informational only — not medical advice.

Body systems

Organs

Neurotransmitters

Related

Where to buy

Popular Vitamin B12 products on Amazon. Not medical advice — talk to a clinician before starting a supplement.

As an Amazon Associate, Neurotransmission earns from qualifying purchases.

Research (16)

Links

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