TB-500 (Thymosin β-4)
A synthetic peptide related to thymosin beta-4, used for injury repair, flexibility, and recovery. Not approved for human use.
Benefits
Why it is used: promoted for soft-tissue repair, flexibility, and reduced inflammation, based mainly on animal and cell studies.
Risks
No human safety data, a theoretical concern about promoting abnormal cell growth, and unregulated sourcing. Banned in sport.
Informational only — not medical advice.
Body systems
Research (6)
- Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance Mendias et al. (2026) PubMed ↗
- Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians Mayfield et al. (2026) PubMed ↗
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions Rahman et al. (2026) PubMed ↗
- Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain Lee et al. (2021) PubMed ↗
- Thymosin beta 4 and the eye: the journey from bench to bedside Sosne (2018) PubMed ↗
- Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications Goldstein et al. (2012) PubMed ↗
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