CBD
CBD (cannabidiol) is a non-intoxicating cannabis compound. Strong evidence supports a purified prescription form for certain rare, treatment-resistant epilepsies, but popular claims for anxiety, pain, and sleep rest largely on preliminary or preclinical data. It is generally well tolerated, though it can interact with other medications by inhibiting liver enzymes, and over-the-counter product quality varies widely.
Too little may be associated with
No deficiency.
Too much may be associated with
Fatigue, GI upset, drug interactions.
Informational only — not medical advice.
Benefits
Non-intoxicating cannabinoid with prescription-grade evidence for certain epilepsies and exploratory use for anxiety, pain, and sleep.
Risks
Can cause drowsiness, diarrhea, and liver-enzyme elevations and inhibits CYP drug metabolism (notably interacting with blood thinners). Product potency and purity vary widely.
Informational only — not medical advice.
Research (6)
- CBD and the 5-HT1A receptor: A medicinal and pharmacological review Alexander et al. (2025) Full text ↗ PubMed ↗
- Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity Rosenberg et al. (2023) Full text ↗ PubMed ↗
- Functional interactions between cannabinoids, omega-3 fatty acids, and peroxisome proliferator-activated receptors: Implications for mental health pharmacotherapies Jung et al. (2022) Full text ↗ PubMed ↗
- The Pharmacological Case for Cannabigerol Nachnani et al. (2021) Full text ↗ PubMed ↗
- Cannabis, Cannabinoids, and Sleep: a Review of the Literature Babson et al. (2017) Full text ↗ PubMed ↗
- Cannabidiol--recent advances Mechoulam et al. (2007) Full text ↗ PubMed ↗
Links
Recovery resources
Help for cbd use and recovery. Not an endorsement or medical advice — see all recovery resources.
- Marijuana Anonymous (MA)
A 12-step fellowship for people who want to stop using marijuana.
Community
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