Polyethylene glycol (MiraLAX)
Osmotic laxative. Draws water into the colon to relieve constipation. Remains primarily in the gastrointestinal tract. No direct brain effect — does not cross the blood–brain barrier.
Benefits
An osmotic laxative that draws water into the colon for effective, non-irritating relief of constipation.
Risks
Can cause bloating, cramping, and diarrhea, and overuse leads to electrolyte imbalance. Generally safe for short-term use.
Informational only — not medical advice.
Body systems
Organs
Where to buy
Popular Polyethylene glycol (MiraLAX) products on Amazon. Not medical advice — talk to a clinician before starting a supplement.
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Research (6)
- Review of Hydroxypropyl Methylcellulose in Artificial Tears for the Treatment of Dry Eye Disease Mysen et al. (2024) PubMed ↗
- Interferons in the treatment of myeloproliferative neoplasms Vachhani et al. (2024) PubMed ↗
- Artificial Tears: A Systematic Review Semp et al. (2023) PubMed ↗
- Medical Management of Constipation in Elderly Patients: Systematic Review Kim et al. (2021) PubMed ↗
- Efficacy and Safety of Over-the-Counter Therapies for Chronic Constipation: An Updated Systematic Review Rao et al. (2021) PubMed ↗
- Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications D'souza et al. (2016) PubMed ↗
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