Omega-3
Essential fatty acids (EPA and DHA), largely from fish oil, that are core structural components of brain-cell membranes and are linked to mood and cardiovascular health.
Benefits
Essential fats (EPA, DHA, ALA) that lower triglycerides and support heart, brain, and eye health.
Risks
High doses can increase bleeding risk and cause GI upset or a fishy aftertaste; source quality and oxidation matter.
Informational only β not medical advice.
Where to buy
Popular Omega-3 products on Amazon. Not medical advice β talk to a clinician before starting a supplement.
As an Amazon Associate, Neurotransmission earns from qualifying purchases.
Research (23)
- [Nutrition in improving sleep quality and fighting insomnia] Ortega et al. (2025) Full text β PubMed β
- The Effects of Omega-3 Supplementation Combined with Strength Training on Neuro-Biomarkers, Inflammatory and Antioxidant Responses, and the Lipid Profile in Physically Healthy Adults Okut et al. (2025) Full text β PubMed β
- The relationship between endometriosis and diet OsmanlΔ±oΔlu et al. (2023) Full text β PubMed β
- Pharmacological interventions for pruritus in adult palliative care patients Boehlke et al. (2023) Full text β PubMed β
- Characterization of the fatty acid profile in the ventral midbrain of mice exposed to dietary imbalance between omega-6 and omega-3 fatty acids during specific life stages Sakayori et al. (2022) Full text β PubMed β
- Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce Sarris et al. (2022) PubMed β
- Mechanistic Insights into the Link between Gut Dysbiosis and Major Depression: An Extensive Review Sonali et al. (2022) Full text β PubMed β
- Associations between Omega-3 Index, Dopaminergic Genetic Variants and Aggressive and Metacognitive Traits: A Study in Adult Male Prisoners Fernandez et al. (2022) Full text β PubMed β
- Functional interactions between cannabinoids, omega-3 fatty acids, and peroxisome proliferator-activated receptors: Implications for mental health pharmacotherapies Jung et al. (2022) Full text β PubMed β
- Role of diet in hyperuricemia and gout Danve et al. (2021) Full text β PubMed β
- Potential depression and antidepressant-response biomarkers in human lymphoblast cell lines from treatment-responsive and treatment-resistant subjects: roles of SSRIs and omega-3 polyunsaturated fatty acids Chukaew et al. (2021) Full text β PubMed β
- Fish-oil supplementation decreases Indoleamine-2,3-Dioxygenase expression and increases hippocampal serotonin levels in the LPS depression model Carabelli et al. (2020) Full text β PubMed β
- Gut-brain Axis and migraine headache: a comprehensive review Arzani et al. (2020) Full text β PubMed β
- Nutricosmetics: A brief overview Dini et al. (2019) PubMed β
- Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality Dariush (2019) Full text β PubMed β
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